Efficacy and side effects of non-denatured type Ⅱ collagen-Chiti News-Chiti Biotech
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Efficacy and side effects of non-denatured type Ⅱ collagen

Non-denatured type II collagen is similar to glucosamine, chondroitin, and MSM. They are all health foods for joints. In empirical medicine, what are the benefits of taking these ingredients? Are there any side effects or contraindications? See the text analysis for details.

What is non-denatured type II collagen?

Undenatured type 2 collagen/UC2/UC-II is a new patented ingredient for bone and joint health care recently. It is mainly extracted from the cartilage of chicken sternum. The special feature is its undenatured (Undenatured) word. , Which means that the original three-dimensional helix structure (triple helix form) can be retained without the usual hydrolytic denaturation process, which is the most biologically beneficial.

Both animal and human experiments have found that after entering the intestinal tract, non-denatured type II collagen can initiate a special desensitization process, also known as oral tolerance.

This process can train immune cells to recognize the correct endogenous cartilage protein molecules in the tissue instead of treating it as a foreign invader, thus preventing a series of inflammatory reactions and devastating attacks (the main cause of bone and joint stiffness and pain). Only a small amount is required to be effective.


What are the recommended empirical effects of non-denatured type II collagen?

1. Good for osteoarthritis

Osteoarthritis is a common joint disease. Although there is no fatal danger, it is also the main culprit for the disability of middle-aged and elderly people

According to clinical and imaging investigations, the prevalence rate of osteoarthritis has increased from 1% under 30 years old, 10% under 40 years old, to 50% over 60 years old. It is a kind of disease that will definitely happen the longer you live. disease.

A double-blind controlled study (for a period of 90 days and 52 patients with degenerative arthritis) found that taking non-denatured type II collagen (UC-II) helped reduce the osteoarthritis index (WOMAC) by 33% , Compared to 14% of glucosamine + chondroitin.

Other indicators such as pain score (VAS score) and pain function index (Lequesne's functional index) also decreased. The UC-II group decreased by 40% and 20%, compared with 15.4% and 6% of glucosamine + chondroitin.

According to this study, it is shown that the non-denatured type 2 collagen (UC-II) has more than twice the effect of glucosamine and chondroitin on the health and improvement of bones and joints. However, due to the small number of samples, more experiments are needed for further verification.

2. Improve joint pain caused by exercise

Exercise is good for cardiopulmonary function, can help lose weight and bring a series of health benefits, but there is also a risk of injury.

Depending on the type of exercise, the common cause is joint injuries caused by gravity. The main causes are wrong training methods, overuse, sudden changes in direction, and height differences.

A double-blind controlled experiment (for a period of 120 days, with 55 healthy adults with no daily symptoms of arthritis) found that compared with placebo, supplementation of non-denatured type II collagen (UC-II) helps to prolong Exercise time (before you feel joint pain), and recover from joint discomfort quickly.

In addition, compared to the baseline, the performance of Knee Extension in the UC-II group was also significantly better than the control group.

This shows that supplementation of non-denatured type II collagen does help improve joint comfort, flexibility and mobility.

Are there any side effects of non-denatured type II collagen?

Based on current clinical research, at the indicated dose, non-denatured type II collagen (UC-II) is a health-care ingredient with high safety. Despite this, potential side effects may occur, including allergies, nausea, heartburn, diarrhea, constipation, fatigue, skin reactions, and headaches.

Safety precautions (taboo)

-) Do not use for pregnant women, breastfeeding mothers, and people with poor liver and kidney function (because the relevant safety is still unknown)

-) Do not use if you have been allergic to eggs or related meat foods (may induce allergic reactions)

non-denatured type Ⅱ collagen

The most popular UC2/UC-II brand recommendation

In recent years, food safety issues in various countries have exploded. What people spend money on is not healthy, but black-hearted goods. Therefore, products made from European and American raw materials with relatively strict quality control have become popular products.

Chiti's non-denatured type II collagen is based on mature technology from Japan and Taiwan, and has an average molecular content of 500 Daltons. It has become a very popular product in the near future and has a very high customer return rate. In addition, Chiti has very mature foreign trade experience. Products can be directly delivered to cities and regions around the world through multiple transportation channels, so that you can enjoy high-quality health products and Raw materials for health products.